The British-Nigerian born boxer knocked out Wladimir Klitschko in the 11th round to secure a stunning victory at Wembley.
The Sun UK reports that the 90,000 boxing fans in the national stadium were on their feet as the Watford man retained the IBF belt and also bagged the WBA and IBO strap.
Klitschko was knocked down in the fifth, and then the tables were turned in round six when Klitschko landed a huge right that floored Joshua.
In the 11th round, Klitschko tasted the canvas twice more, until the referee dived in to wave off the fight as Joshua sealed victory in one of the best heavyweight fights of all time.
Speaking in the ring after his momentous victory, Joshua said: “What can I say, first and foremost, 19 and 0, three-and-a-half years in the game.
“I’m not perfect but I’m trying. I want to give a shout out to all my trainers, to 90,000 people in the arena, and lastly, as boxing states, you leave your ego at the door and you respect your opponent.
“So a massive shout to Wladimir Klitschko. In terms of the boxing hall of fame he is a role model in and out of the ring.
“I have nothing but respect for anyone who steps in the ring.